Advanced life-science instrumentation

See what bulk measurements miss.

Rhei BioTech develops advanced life-science instrumentation for single-particle and single-cell analysis, integrating microfluidics, optical detection, real-time processing and intelligent manipulation.

Microfluidics · optical detection · real-time processing
Concept illustration — controlled particle flow through an instrument-style optical interrogation region.

Rhei BioTech develops advanced life-science instrumentation for single-particle and single-cell analysis.

Focus
Resolve heterogeneity
Approach
Integrated workflows
Location
Hangzhou, China
The measurement gap

Bulk measurements compress complexity into a single average.

Biological samples are heterogeneous. When signals are pooled, rare populations and particle-to-particle differences can disappear inside the mean.

Population / ensemble vs individual eventsConcept illustration
Individual events Distinct subgroup– – Ensemble average
Schematic spread and subgroup / No measured values or experimental data are represented.
01

Hidden distributions

An average can describe the center while concealing the population around it.

02

Rare subpopulations

Low-abundance particle or cell groups may be difficult to distinguish in pooled measurements.

03

Lost individuality

Particle-level signals can reveal variation that ensemble-level readouts do not retain.

NanoSpec AIIn Development

Intelligent single-particle analysis and sorting.

NanoSpec AI is Rhei BioTech’s flagship platform in development for intelligent single-particle analysis and sorting.

It integrates microfluidic handling, optical detection, real-time signal processing, intelligent analysis and active sorting or manipulation.

NanoSpec AI / system architectureMeasurement → decision → action
Sample inletOptical interrogationSorting junction / outputs
  1. 01
    Sample handlingMicrofluidics
  2. 02
    Optical interrogationOptics
  3. 03
    Signal acquisitionElectronics
  4. 04
    Event processingReal-time processing
  5. 05
    Event interpretationIntelligent analysis
  6. 06
    Selective actionSorting
Control feedback

Event-linked processing and interpretation inform the intended sorting or manipulation step.

Fig. 01 Concept illustration. NanoSpec AI architecture is in development; geometry is schematic and does not specify a physical instrument configuration.
Technology platform

One integrated measurement-and-sorting workflow.

Fluidics, optics, electronics and computation connect individual-event measurement to interpretation and selective action.

  1. 01
    Microfluidics

    Precisely structured fluid handling at small scales.

  2. 02
    Optical detection

    Individual-event signal capture as a platform capability.

  3. 03
    Electronics

    Signal acquisition and coordinated instrument control.

  4. 04
    Real-time processing

    Connect measured events with timely computation.

  5. 05
    Intelligent analysis

    Interpret event information and population structure.

  6. 06
    Sorting

    A developing path from interpretation to selective action.

NanoSpec AI / system architectureMeasurement → decision → action
Sample inletOptical interrogationSorting junction / outputs
  1. 01
    Sample handlingMicrofluidics
  2. 02
    Optical interrogationOptics
  3. 03
    Signal acquisitionElectronics
  4. 04
    Event processingReal-time processing
  5. 05
    Event interpretationIntelligent analysis
  6. 06
    Selective actionSorting
Control feedback

Event-linked processing and interpretation inform the intended sorting or manipulation step.

Fig. 01 Concept illustration. NanoSpec AI architecture is in development; geometry is schematic and does not specify a physical instrument configuration.
HyperDrop system with controller, chip fixture and workflow consumables
HyperDrop system / Controller, chip fixture and workflow consumables.
HyperDropAvailable

Precision microfluidic tools for droplet generation and fluid control.

HyperDrop is Rhei BioTech’s commercial microfluidic product family for droplet generation and precision fluid control, combining controllers, microfluidic chips and workflow consumables.

System bundleAR-ONE-1000AR-FOUR-5000ChipsOils & consumables
View the HyperDrop family
Application areas

Focused on workflows where heterogeneity matters.

Explore particle-level research questions and controlled droplet workflows.

NanoSpec AI

Single-particle analysis platform

Concept illustrations / Research context, not application-validation evidence.

Technical resources

A growing record of methods and validation.

Platform and product-family overviews are available below. Approved figures, methods, datasheets and validation notes will be published as they become available.

Publication status Public validation data and downloadable datasheets are not yet available.

Company

Building instruments for a more resolved view of biology.

Rhei BioTech develops advanced life-science instrumentation for single-particle and single-cell analysis, integrating microfluidics, optical detection, real-time processing and intelligent manipulation.

Based in
Hangzhou, China
Portfolio
NanoSpec AI · HyperDrop